Facts about Xeljanz/Xeljanz XR (tofacitinib), Olumiant (baricitinib), and Rinvoq (upadacitinib), Additional Information for Health Care Professionals, National Institute of Arthritis and Musculoskeletal and Skin Diseases: Rheumatoid Arthritis, National Institute of Arthritis and Musculoskeletal and Skin Diseases: Psoriatic Arthritis, National Institute of Diabetes and Digestive and Kidney Diseases: Ulcerative Colitis, Genetic and Rare Diseases Information Center: Polyarticular onset juvenile idiopathic arthritis, National Heart, Lung, and Blood Institute: Heart Attack, National Heart, Lung, and Blood Institute: Stroke, National Heart, Lung, and Blood Institute: Venous Thromboembolism, FDA: Information on Tumor Necrosis Factor (TNF) Blockers, The FDA's Drug Review Process: Ensuring Drugs Are Safe and Effective, Think It Through: Managing the Benefits and Risks of Medicines, Discomfort in the center of your chest that lasts for more than a few minutes, or that goes away and comes back, Severe tightness, pain, pressure, or heaviness in your chest, throat, neck, or jaw, Unusual pain or discomfort in your arms, back, neck, jaw, or stomach, Shortness of breath with or without chest discomfort, Weakness in one part or on one side of your body, Leg pain or tenderness, or red or discolored skin in the painful or swollen leg or arm. "Shh! The altered commercials include the ones for the Lizard Flare and the Yummy Can (don't ask). for your pointless bitchery needs. Xeljanz is also approved to treat psoriatic arthritis, ulcerative colitis, and polyarticular course juvenile idiopathic arthritis. R531-As long as you clueless straight boys keep making them, we'll keep watching them. However, if you are a current or past smoker, or have had a heart attack, other heart problems, stroke, or blood clots in the past, you should tell your health care professional as these may put you at higher risk for serious problems with these medicines. These medicines are part of a class called Janus kinase (JAK) inhibitors and are used to treat certain serious, chronic, and progressive inflammatory conditions. Other JAK inhibitors have not been studied in similar large safety clinical trials, so the risk with these medicines has not been evaluated. All the cool kids are overusing the word "disrupt". By using iSpot.tv, you accept our, Real-Time Ad Measurement Across Linear and CTV, Marketing Stack Integrations and Multi-Touch Attribution. Drug manufacturers spent $17.8 billion on direct-to-consumer advertising (DTCA) for 553 drugs from 2016 through 2018, and spending was relatively stable at about $6 billion each year. "It you were stationed at Camp Lejeune between 1952 and . McDonalds has an ad showing a backyard party - closeup on a woman and her gay friend looking dismal. site without all this bureaucratic nonsense, Anyway, as an elderly guy, 60 I guess, he moved to New York (after being a theatre actor I think) -- anyway, he left his phone number in the phone book and encouraged just anybody to call him as he lived alone and loved to talk to people - just anybody. Is the destination at the end the Enchantment. But like she has to know he does it himself because it's not like she's lifted one single figure to help him with a god-damned thing since mom died. R336, those ads need to go full-on tragedy porn and show a dead lady with her eyes chewed out by dear Bitsy. A lot of people react to the Molly Shannon Lenda commercial. Given where we are right now, it's has some scary aspects to it. Tom Selleck getting defensive about reverse mortgages. I'm sure I knew that once but my eldergay brain is slowly failing me. As if the Progressive ads with Flo weren't bad enough, now we have one featuring the short girl who was a background character now in front and who has one of THE most irritating vocal fries ever. Thank God the Sunshine On My Shoulders baby in grandma's lap spot has been pulled. You know that commercial or product placement that's twice as loud as all the others and is that one always gets an instant "mute" from my remote. When was the current RINVOQ commercial filmed on Nimitz Way ? What are you on about r261. He should make that cackle his trademark and do it in every commercial. 2020 Concacaf League, In the new chik fil a commercial the girl voice over describes their chicken sandwich as scrum diddly umptious. All I was buying were a bunch of Torino's frozen pizza and like a case of cat food. R80, I assume that the voice of the St. Bernard in the Chewy commercial is based on Mel Blanc's voice of Willoughby, the big dumb dog in the 1940 Warner Bros. cartoon "Of Fox and Hound". I'm pretty sure they'd manage to champion on. Here is just a smattering of comments we have received. The castle featured in the Eliquis Commercial entitled 'Travel' is the 1929 Plaza de Espaa in Seville. She looks like Caitlyn Jenner now. Sorry to be so off-topic but another eccentric I miss is Quentin Crisp. Pass me a large bucket. Are they out of their fucking minds? They should have hired two puppets. R59, that's Nina Simone singing that horrid song on the vitamin commercial. I have boxer shorts with the same pattern as her wrap. Each and every Camp Lejeune lawsuit ad. Never in my wildest imagination did I ever expect to see a trans man with the identical features of a Ray Ramono like in the new Audible commercial. [quote]I also hate the Grifter Christian commercial that is all about sending money to help the elder Jews. The yoga pants commercial or whatever it is with a fat black chick launching herself into the air and falling back down in slow motion. The canisters suck, btw. Counsel patients about the benefits and risks of these medicines and advise them to seek emergency medical attention if they experience signs and symptoms of a heart attack, stroke, or blood clot. (I listen to the news -- 1010 WINS -- in the kitchen). and no one playing the Colonel. Stephanie Courtney plays progressive Flo on the Big Bang theory.. BK thinks for a minute and then says, "Wait. Its a big part of why health care is so expensive, because its the fancy, high-tech things that get marketed.. . Joan Collins late ex-husband ? "Butt suds." They havent had any decent in their original programming since Chappell besides their obvious cash cow. You must create a shipping manifest by following the steps outlined on the "Manifest" tab Google years ago used to have some gay comm that they would run. The bratty little girl in the Golden Corral commercial who berates her dad. Another for the anti tobacco commercials with the black poet quoting how their main target is the black and the stupid. What gives? There is currently no information about the safety and effectiveness of RINVOQ in children. DTC prescription drug advertising increased from $1.3 billion (79000 ads) to $6 billion (4.6 million ads [including 663000 TV commercials]), with a shift toward advertising high-cost biologics and cancer immunotherapies.. Last time I did that, he walked into the cat carrier around 8 am. And here I thought they were saying they were not embarrassed to show their psoriasis skin anymore. I dont get why were walking on eggshells all of a sudden now. Thank you for taking the time to alert us to potentially misleading promotion. that fat ethnic tovala bitch who shakes her lard filled bazooms as she creams over the thought of getting fatter with TOVALA !!!! Yes, it is vile, R154. There's about three kids in room playing. Im hissing just thinking about it. The woman says her ". Like wiping their nose on their T-shirt is so bizarre? R159 Thank you! You can contact the top cop! More like Hamm on rye. I don't know why, but there's something about her face that makes me want to punch it. Then the teen girl's sister bursts in with a pair of underwear and tells her sister to put these on instead, because they'll absorb all her blood and she won't need a tampon at all. Ok assholes, there is a new fall/winter edition now. the man has severe osteoporosis and shrunk a half foot or c.) she is remembering some other hot dude from years ago while dancing with the old man. Everybody in drug commercials is fat now. The Rexulti commercial. I have a longtime female friend of Peruvian descent, the person in the Kleenex ad resembles her brother. The cutesy Chic-Fil-A commercials about a company that is vehemently anti-gay/trans. But spin it in the direction you want to get your point across. That pain in the ass Kevin Hart promoting some online betting app. I think Mike Huckabee is connected to those ads, r76, so for sure its some kind of scam. Most patients were female (78 percent) and Caucasian (77 percent). The whole thing is such a scam. We are also limiting the use of these medicines to certain patients who are not treated effectively or who experience severe side effects with another type of medicine used to treat serious inflammatory conditions called tumor necrosis factor (TNF) blockers. She's the new CEO of Pacific Gas & Electric, the monopolistic public utility that has been through Chapter 11 bankruptcy and convicted of crimes for causing wildfires that destroyed towns and forests while killing people. Actors in the Hunger Games spent time in Hawaii filming many of the water scenes in the Quarter Quell on Oahu. I don't get it, is it supposed to be funny? Not meee!, while a million pedophile and pederast hearts n palms begin a thumpin. I think that would make a funny SNL skit. Any drug commercial where people are smiling without showing their teeth. Helena Christina Mattsson. Hello and thank you for being a DL contributor. Lume deodorant you can use on your pits to the balls.. of your feet. Casting directors don't necessarily want a more recognizable commercial face. GAO also found that nearly all DTCA spending was on brand-name drugs, with about two-thirds concentrated on 39 drugs, about half of which entered the market from 2014 through 2017.. It went from 11.9% of total marketing dollars in 1997 to 32% of the total in 2016. With the Camp Lejeune lawsuit commercials and infomercials running rampant nonstop, imagine whats gonna happen when Flint Michigan finally gets the justice those people deserve. STOP the Intel spots with that fucking don't worry, be happy song. That chanting at the end of the commercial is creepy and annoying. Theres one preachy commercial and I dont even really know who its geared towards. I keep seeing this immensely annoying commercial for some migraine drug or something called Emgality. The data showed evidence of a dose-dependent increased risk for MACE, all-cause mortality, and thrombosis at both doses of Xeljanz when compared to treatment with TNF blockers. Haven't read all the replies so forgive me if this has been mentioned but what about that awful fast food chicken place where the little girl is dismayed that her daddy has "fisted" her brother? America needs more eccentrics! This other time a woman paid for my groceries. The Life Alert one that begins with when the elderly fall. [italic] Down With Rybelsis ! According to the latest data from real-time ad trackers at iSpot, AbbVie spent a whopping $39.2 million on TV ads for Rinvoq in July. Probably due to complaints from R223 and others. Ew. Do you feel violated, Crystal Minkoff? This 2001 Hollywood blockbuster filmed in Hawaii for just five weeks, and used authentic World War II planes belonging to various air museums alongside real battleships. I'm certain he's just playing himself in everyday life. Here is a link to one commercial for this popular drug. Yes, R275! A commercial for Rinvoq promotes this drug for treating eczema (atopic dermatitis). Who appears in the CarShield TV commercial? GREAT EXAMPLE, DAD. If that time machine thing worked in yet another paving stone commercial, the whole barbecue would be underwater. The fucking car commercial with the parents coming home from a PTA meeting and are so afraid of their teenaged daughter, Mom promises her use of the car to end the little shit's interrogation of them. On January 14, 2022 the FDA issued an update on some very serious warnings for a category of drugs called Janus Kinase (JAK) inhibitors. Current or past smokers are at higher risk for lymphoma and lung cancer. Its your fake trolling asses that piss me off. Before using Rinvoq, please consult your doctor to determine if it is right for you. I gather he's one of those so-caller "influencer," whatever that is. Tim Allen - Pure Michigan. What they may not realize, however, is how much the American public dislikes these ads. It's so fake. People 50 and older with at least one risk factor for heart disease have higher risks. In addition, women have a greater soybean intake due to its role in preventing ovarian cancer, so it is possible that this accounts for some of the disparity. To help FDA track safety issues with medicines, we urge patients and health care professionals to report side effects involving Xeljanz/Xeljanz XR, Olumiant, Rinvoq, or other medicines to the FDA MedWatch program, using the information in the Contact FDA box at the bottom of the page. There's no info online what gender the person in the Kleenex snot bubble ad happens to be. Worst possible voices to match those dogs. In addition to the specific disclosure requirements, advertisements cannot be false or misleading or omit material facts. Serious infections or blood clots, some fatal, cancers, including lymphoma and skin cancer, death, heart attack, stroke and tears in the stomach or intestines occurred. The announcer talks about kids struggling to find their career path: "BUT NOT OUR SYDNEY!". The singing coils of pubic hair commercial. The drive time shield or whatever where the dude talks about his failed plans of a bubble bath and pedicure for the afternoon. Also, the Chevy Volt commercial where the pregnant woman is having the charger installed in her garage by another woman and you're led to believe they're talking about how easy it is to have a baby, but instead they're discussing charging the car. Enough already! Zt 0609 Sprint Run, That's also Nina Simone singing on that One A Day vitamin commercial. Sick to death of the DuckDuckGo commerical using The Police's song Every Breath You Take.. The model looked in her element as she strolled on the beach, soaking up the sun. 484 since its liberal California where they mistake open mindedness for being just plain gullible theres more of a chance the majority of these props will pass. They way theyre always targeting schools for example, 8 times out of 10 times these (as I like to call them) Mrs. Lovejoy from the Simpsons think about the children props pass. assessing KIA commercial on the Emmys last night. Those hideous fraus complaining they can't shit. [quote]my comment wasn't about the commercial asshole. .get and go just got up and went." Why is Jon Hamm in all those Progressive ads, is he desperate for cash? Ok so shouldnt that mean every school district in CA look like West Beverly from 90210 with radio stations in tact and every amenity imaginable at the students disposal? Wait!" When it first started running I would stare in horror wondering how they could choose such an unfortunate looking spokesman. 855-543-DRUG (3784) and press 4 druginfo@fda.hhs.gov Report a Serious Problem to MedWatch Complete and submit the report Online. R72 its called live tv and a lot of people watch it everyday. Patients in the trial were required to be 50 years of age or older and have at least one cardiovascular risk factor. I suggested you create your own thread so you'd stop bitching on this thread. Well the first guy taking his shirt off was gorgeous and had a rockin washboard but it went downhill fast. R74, the sister asked Flo to come over to talk about insurance because she couldn't get her baby to sleep. DTX Trailblazers. Talk to your health care professional if you have any questions or concerns. Health care professionals and patients can access the approval letters and latest prescribing information in Drugs@FDA: Xeljanz, Xeljanz XR, Olumiant, Rinvoq. If I see one more "dripping your urine into a plastic bottle while you sleep" commercial, I'm gonna throw up. Many people might think that if they took Lipitor they could reduce their chances of developing a heart attack by more than one third over five years. Lil Caleb better watch his ass now that lil Sebastian is grifting for the Shriners. Everyone complains about ads, but no one does anything about them. The one Gary Busey used to call the antichrist? It is important to know that people respond differently to all medicines depending on their health, other medicines they are taking, the diseases they have, genetic factors, and many other factors. But I do hate their cloying, manipulative commercials. The very ugly and fat fuck named John going through life stages with some medication. R277 / R279 Yes, the Lending Tree commercials are being shown in heavy rotation. The man is attending, what I assume, is a backyard barbecue. Lol that Nutrisystem commercial with Marie Osmond is like it's 50. [quote]One that I'm loving is the True Classic Tee commercials. The Safelite commercial where the woman is on her MORNING walk with friends. This condition often causes redness, itching or rash. You can sign up for email alerts about Drug Safety Communications on medicines or medical specialties of interest to you. Source: disney.fandom.com. Non-binary them? In 1984 drug companies responded to Representative John Dingell from Michigan about DTC drug advertising: The view of the Upjohn Company is that the direct advertising of prescription pharmaceuticals to consumerswould be detrimental to the pharmaceutical industry and, more importantly, a potentially disruptive element in our medical delivery system as a wholeOur view is that there is a vast difference between education and promotionProduct specific consumer ads could increase costs., We have serious concerns about proposals to allow advertising directly to patients. This commercial is on during the local news every night. Dont watch this movie if you are planning to hike the Kalalau Trail on Kauais North Coast anytime soon, since a lot of the violence-filled movie is based there. I was watching Hulu today and saw two Progressive ads with Flo and Jon Hamm. Caleb must be 40 by now. Any of their commercials. It discusses serious infections like tuberculosis and invasive fungal infections along with bacterial, viral, herpes zoster, and other infections due to opportunistic pathogens., Then there are the major adverse cardiovascular events aka MACE. Tim Allen is the guy who voices the Pure Michigan commercials. Frankly, I HATE TV ads for drugs. You should be pleased! She then gets a phone call from Lilly, who is at school. so true. Submissions should come only from actors, their parent/legal guardian or casting agency. The narrator has a very annoying lisp. The Jurassic Park dinosaur tie-ins with other commercials. Santa in the ICU with a monkeypox variant? R217 Be sure to check out this thread.

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